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Development pipeline
Four medicines and three surgical platforms, built in eighteen months on $90 million of research and development. Updated 31 July 2026.
3Medicines in Phase 1
1Medicine in IND-enabling studies
1Device FDA cleared
2Devices in development
Medicines
| Candidate | Indication | Therapeutic area | Modality | Stage |
|---|---|---|---|---|
| BX-101 | Advanced solid tumours (KRAS G12D) | Oncology | Targeted protein degrader, oral | Phase 1 |
| BX-204 | Fibrostenotic Crohn's disease | Immunology & Inflammation | TL1A antagonist, oral | Phase 1 |
| BX-412 | Elevated lipoprotein(a) | Cardiometabolic | siRNA, subcutaneous | Phase 1 |
| BX-308 | Amyotrophic lateral sclerosis | Neuroscience | Antisense oligonucleotide, intrathecal | IND-enabling |
Surgical technology
| Platform | What it does | Intended use | Status |
|---|---|---|---|
| Lumavue™ | Real-time tissue perfusion imaging | General, colorectal and reconstructive surgery | FDA 510(k) cleared |
| SealWeave™ | Bioresorbable staple-line sealant | Gastrointestinal and thoracic surgery | Design verification |
| Axion OR™ | Robotic soft-tissue instrument platform | Minimally invasive abdominal surgery | Prototype / preclinical |
Important: BX-101, BX-204, BX-308
and BX-412 are investigational and have not been approved by any regulatory authority. Their
safety and efficacy have not been established. SealWeave and Axion OR are investigational
devices, limited by law to investigational use. This page is informational and is not an offer
to sell or a solicitation to buy securities.
How the portfolio got here
2026
Into the clinic
BX-101, BX-204 and BX-412 all entered Phase 1 within a nine-month window. Lumavue received FDA 510(k) clearance in July.
2026
Stopped
Two discovery programs — a second-generation degrader series and an energy-based sealing device — were discontinued after failing the candidate-selection gate. The rationale for both is in our annual research summary.
2025
Founded and built
Company incorporated in March, Jupiter laboratories opened in August, Palm Beach Gardens engineering facility opened in November.